從圖中可見，癌細胞所在的環境非常複雜。515Please respect copyright.ＰＥＮＡＮＡ6BzbpwSQnr
癌細胞附近不只有著各種細胞，其就近的血管大多處於參差不齊的狀態，導致營養及氧氣難以順利到達癌細胞裡頭。515Please respect copyright.ＰＥＮＡＮＡumr6ZGl8HQ
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在這種「逆境」之中，癌細胞究竟有何手段求生呢?515Please respect copyright.ＰＥＮＡＮＡigZXUxeaDh
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(圖2)在導管胰腺癌中，科學家發現癌細胞的所在位置含有大量名為CAM的細胞。515Please respect copyright.ＰＥＮＡＮＡ2PuU1hbtKJ
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經一系列的研究後，科學家發現這些細胞竟然是協助癌細胞長大的好幫手。515Please respect copyright.ＰＥＮＡＮＡ3qLLRuDv6p
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(圖3)圖中為癌細胞如何利用周遭的CAM細胞供養自己的機制。515Please respect copyright.ＰＥＮＡＮＡHIG4FUvgYa
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在營養短缺的環境下，癌細胞迫使周遭的細胞分解蛋白質供自己所用，從而渡過難關及繼續在逆境中成長。515Please respect copyright.ＰＥＮＡＮＡmAQQ4VhHdE
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在老鼠的動物模型中，若然抑制CAM細胞進行自噬作用，癌細胞的體積的確是有所縮小，得以證實癌細胞會用盡身邊的一事一物從而壯大自己，在先天資源短缺的環境下亦能「自肥」。515Please respect copyright.ＰＥＮＡＮＡzcylUSGf1s
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。515Please respect copyright.ＰＥＮＡＮＡNOZjjVOJ8o
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Ref1:https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(17)30102-2515Please respect copyright.ＰＥＮＡＮＡUzaT0jlMao
Ref2:https://pubmed.ncbi.nlm.nih.gov/27509858/515Please respect copyright.ＰＥＮＡＮＡAO3hvCF7KE
