做運動有助減肥，就等同721事件包含警黑合作成份一樣，是無容置疑的事情。1272Please respect copyright.ＰＥＮＡＮＡJhC3g8x0vl
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而本篇文章將嘗試以簡淺及略微深入兩種手法，以科學角度解釋做運動如何有助減肥。1272Please respect copyright.ＰＥＮＡＮＡMz3L9LpUvu
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（圖2）要用一句話來概括運動如何有助減肥的話，那就是運動能夠調教身體的肌肉細胞更有傾向及更有效率分解身體的脂肪。1272Please respect copyright.ＰＥＮＡＮＡHTFFXQdOCt
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當我們持績進行帶氧運動的話，脂肪便會被分解。而被分解的脂肪會經由血液循環系統抵達肌肉部位，在氧氣、水及各蛋白酶的幫助下，脂肪會在肌肉細胞裡轉化成為細胞所需的能源(ATP)，支撐運動所需的消耗。1272Please respect copyright.ＰＥＮＡＮＡGNIrGqp5zg
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（圖3）綜合現今真實人類研究的數據及主流新陳代謝理論的話，不論男女，帶氧運動會對數個與脂肪新陳代謝有關的蛋白酶作出轉變。1272Please respect copyright.ＰＥＮＡＮＡXSZUe54xqi
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當脂肪來到肌肉細胞外部的時候，位於肌肉細胞外部表面的mLPL(muscle lipoprotein lipase）會將脂肪分解成為更簡單的結構，從而使脂肪結構得以進入細胞內層（cytoplasm)。1272Please respect copyright.ＰＥＮＡＮＡpOs2TJXg4u
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有長期運動習慣的人士，運動時候的mLPL最大功率會比沒有運動習慣的人士為高（Ref1,2)。1272Please respect copyright.ＰＥＮＡＮＡZvoYiiWa6n
同時間，有研究指出進行為期8星期的帶氧運動的話，mLPL的功率會增加40-70%左右（Ref3,4)。1272Please respect copyright.ＰＥＮＡＮＡCtGJ23Aj09
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這顯示出持續運動有助肌肉細胞更有效率吸收脂肪。1272Please respect copyright.ＰＥＮＡＮＡcdintzzyAL
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脂肪結構進入細胞內層後，將會進行一系列的化學反應，然後再經由CPT1蛋白酶的幫助下進入mitochondria；1272Please respect copyright.ＰＥＮＡＮＡj9Zv7KNyZc
mitochondria是真正將脂肪結構轉化成為ATP能源的主要地方。1272Please respect copyright.ＰＥＮＡＮＡ8mHahvKif0
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研究顯示，有運動習慣的人士，運動時候的CPT1最大功率會比沒有運動習慣的人士高出20-90%不等（Ref5,6,7)。1272Please respect copyright.ＰＥＮＡＮＡx9TYEuQqV7
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而當沒有運動習慣的人士持續進行8個月的帶氧運動後，CPT1的功率會比之前高出250%有多（Ref8)。1272Please respect copyright.ＰＥＮＡＮＡyRakcVBqsF
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脂肪結構進入mitochondria後，四步化學反應會將它們變成為更簡單的結構（acetyl-CoA)，其中之一步將依靠HAD蛋白酶執行。1272Please respect copyright.ＰＥＮＡＮＡrfcrx5MYoD
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有研究指出持續數星期運動會促使HAD最大功率增加20-40%(Ref9,10)。而持續進行6星期HIIT運動（高強度間歇訓練，High-intensity interval training)亦會使HDA最大功率增加20-30%(Ref11,12)。1272Please respect copyright.ＰＥＮＡＮＡvmE2TPHt6W
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脂肪結構變成為acetyl-CoA後，一系列的化學反應會再作進行，最後才能夠變成為ATP能源。1272Please respect copyright.ＰＥＮＡＮＡkxDYGCWfOP
CS蛋白酶有份參與在其中一道的化學反應，而有著恆常運動習慣的人，其CS功率亦比沒有運動習慣的人士高出約33%(Ref13)。1272Please respect copyright.ＰＥＮＡＮＡKp1Y4PrG00
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（圖4）之於糖份新陳代謝方面，裡頭有著與脂肪新陳代謝重疊的化學反應步驟。1272Please respect copyright.ＰＥＮＡＮＡccByr9LsG7
而長期運動的人士擁有比較高的PDK4功率（Ref14)，能阻截糖份在mitochondria轉化成為ATP能源，改以在細胞內層(cytosol)進行，好讓脂肪能盡情地在Mitochondria裡轉化成為ATP能源。1272Please respect copyright.ＰＥＮＡＮＡpwrf1wGHJw
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總括而言，持續進行帶氧運動的話，肌肉細胞會自動調節更有效率地分解脂肪，同時亦會傾為改用脂肪而非糖份作為ATP能源的原料。1272Please respect copyright.ＰＥＮＡＮＡJDCxJ4uz46
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這次深入中出嘗試加入了一些可能較難理解或較為沉悶的資料，若果反應未如理想的話，下篇將會調節回平日的深入淺出方法繼續探討各科學問題。1272Please respect copyright.ＰＥＮＡＮＡS709h6Ghbq
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若果大部份人覺得無問題的話，下篇將會以同等的方式講解一下運動後的數小時應否進食。1272Please respect copyright.ＰＥＮＡＮＡ0OSkDEKcya
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如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。1272Please respect copyright.ＰＥＮＡＮＡMjNzTrlyNU
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Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc1272Please respect copyright.ＰＥＮＡＮＡOD7wN623QG
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同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。1272Please respect copyright.ＰＥＮＡＮＡk4Q27jA9DH
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Link:1272Please respect copyright.ＰＥＮＡＮＡMvmvQM6lgw
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio1272Please respect copyright.ＰＥＮＡＮＡcXcnYf8zNM
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有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。1272Please respect copyright.ＰＥＮＡＮＡ8PSSujMBrY
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Ref1:https://pubmed.ncbi.nlm.nih.gov/15155715/1272Please respect copyright.ＰＥＮＡＮＡwrFobnq2JW
Ref2:https://pubmed.ncbi.nlm.nih.gov/212665/1272Please respect copyright.ＰＥＮＡＮＡrtgYrS3hSd
Ref3:https://pubmed.ncbi.nlm.nih.gov/6667282/1272Please respect copyright.ＰＥＮＡＮＡiIcBqsM7uv
Ref4:https://pubmed.ncbi.nlm.nih.gov/2643634/1272Please respect copyright.ＰＥＮＡＮＡLiYXJw9h0T
Ref5:https://pubmed.ncbi.nlm.nih.gov/11912554/1272Please respect copyright.ＰＥＮＡＮＡmCWUDXgwnL
Ref6:https://pubmed.ncbi.nlm.nih.gov/9655768/1272Please respect copyright.ＰＥＮＡＮＡYWrtUabR0M
Ref7:https://pubmed.ncbi.nlm.nih.gov/10710500/1272Please respect copyright.ＰＥＮＡＮＡUhpEPBa4zm
Ref8:https://pubmed.ncbi.nlm.nih.gov/16464906/1272Please respect copyright.ＰＥＮＡＮＡe3uHNSqQkF
Ref9:https://pubmed.ncbi.nlm.nih.gov/22235293/1272Please respect copyright.ＰＥＮＡＮＡtQBv5EsGDc
Ref10:https://pubmed.ncbi.nlm.nih.gov/19106247/1272Please respect copyright.ＰＥＮＡＮＡyuLttIDnIK
Ref11:https://pubmed.ncbi.nlm.nih.gov/19088769/1272Please respect copyright.ＰＥＮＡＮＡ5PxRXTD0Pz
Ref12:https://pubmed.ncbi.nlm.nih.gov/17991697/1272Please respect copyright.ＰＥＮＡＮＡZEPC2hsDQA
Ref13:https://pubmed.ncbi.nlm.nih.gov/25057335/1272Please respect copyright.ＰＥＮＡＮＡOzsWSC4VcC
Ref14:https://pubmed.ncbi.nlm.nih.gov/15020699/1272Please respect copyright.ＰＥＮＡＮＡm4pXr4buom
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