染上武肺及注射mRNA武肺疫苗,兩者均會使身體產生對應武肺的抗體。但兩者之間所產生的抗體數量,又會否有所分別呢?693Please respect copyright.PENANAo64YwLF8O2693Please respect copyright.PENANA0LuKRNSmh3
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(圖2)有科學家分別對比染上武肺人士(染病111-273日後)及注射mRNA疫苗人士(0-200日後)體內對抗武肺S蛋白的抗體,發現染上武肺人士的抗體數量分佈頗為不一,可概括分成高中低(+++,++,+)三大類別。693Please respect copyright.PENANApLinjNGdBI693Please respect copyright.PENANAnvKjZV4hWo
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而注射疫苗人士的體內抗體在數量上,與武肺人士的高類別數量非常接近。693Please respect copyright.PENANABXcM0iOhIA
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(圖3)可能是較為有趣的是,注射疫苗人士的體內抗體,有著能抵抗兩款常見導致感冒的病毒(OC43及HKU1)S蛋白質的能力。693Please respect copyright.PENANA1FPuMEq8KW
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這有可能為注射人士帶來些許抵禦該兩隻感冒病毒入侵身體的能力,而染上武肺人士的體內抗體是否有著同樣功效,研究並沒有透露。693Please respect copyright.PENANAQWxQgbsrPR
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(圖4)研究同時亦發現,注射疫苗人士的體內抗體,大多是由不具中和力的抗體所組成(66-95%),這到底會否引致ADE副作用,還需要一定的研究測量。693Please respect copyright.PENANA6if1W6Uofl693Please respect copyright.PENANACfaJ8iBx9c
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而染上武肺人士的體內抗體,其具中和力及不具中和力的分佈,研究並沒有詳細透露。693Please respect copyright.PENANAWpsiDc22T0
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Ref1:https://www.cell.com/cell/fulltext/S0092-8674(21)00706-6693Please respect copyright.PENANAoLvYmLmwXu