因人而異，膀胱/尿袋 (Urinary Bladder)一般來說可以儲存300-500ml尿液。1065Please respect copyright.ＰＥＮＡＮＡowGf4GzQ2N
1065Please respect copyright.ＰＥＮＡＮＡhYwtLTDVjj
1065Please respect copyright.ＰＥＮＡＮＡRfxk4TFuvR
尿液的其中一個功能，就是將體內的毒素或細菌排出，而膀胱經常有大量尿液儲存，為罪惡的蘊藏之所，體內的警署。1065Please respect copyright.ＰＥＮＡＮＡbIBRMc9YEF
1065Please respect copyright.ＰＥＮＡＮＡaYoOda4YrD
想深一層，身體的細菌經由尿液聚首一堂，膀胱豈不是非常容易令受到感染?1065Please respect copyright.ＰＥＮＡＮＡie7O5rgjJz
1065Please respect copyright.ＰＥＮＡＮＡpxn1l4Puwq
（致病的細菌及毒素亦可從糞便排出）1065Please respect copyright.ＰＥＮＡＮＡLXDhMx5VIS
1065Please respect copyright.ＰＥＮＡＮＡZ6pvfTSlmo
1065Please respect copyright.ＰＥＮＡＮＡery2zY1But
（圖2）尿調理素(Uromodulin/Tamm–Horsfall Protein)是尿液其中一種常見的主要蛋白，主要在腎臟管道生產。1065Please respect copyright.ＰＥＮＡＮＡtCsfwd72oC
1065Please respect copyright.ＰＥＮＡＮＡl85lmcyjWB
1065Please respect copyright.ＰＥＮＡＮＡ0xHZljiVZC
它被認定為有抵禦細菌感染的作用，但一直以來也沒有充分的證據得以證明。1065Please respect copyright.ＰＥＮＡＮＡRBw2CeUi7u
1065Please respect copyright.ＰＥＮＡＮＡnIrBNkROJX
近日，有科學家利用最新的電子顯微鏡技術及各種實驗輔證（Ref1)，終於確立得到尿調理素抵禦細菌感染的功能。1065Please respect copyright.ＰＥＮＡＮＡGOJy7Tcbe3
1065Please respect copyright.ＰＥＮＡＮＡrncP6JzllL
（圖3）先簡單重溫一下細菌的外部結構，今次我們會特別著重提及Pili，它賦予細菌與外部接觸的能力。1065Please respect copyright.ＰＥＮＡＮＡb47W2B1yav
1065Please respect copyright.ＰＥＮＡＮＡyb1nCh16vU
1065Please respect copyright.ＰＥＮＡＮＡpJqEdlV1IJ
1065Please respect copyright.ＰＥＮＡＮＡU5tLtFawg3
1065Please respect copyright.ＰＥＮＡＮＡYiwOUcrzP1
（圖4）左邊是文中的圖片，黃色箭嘴頭所指示的就是細菌的pili，它能夠與uromodulin建立非常穩定的連結；1065Please respect copyright.ＰＥＮＡＮＡKDVRhDXPtH
箇中的連結需要糖份組織的幫助。1065Please respect copyright.ＰＥＮＡＮＡu7Kz09OsnW
1065Please respect copyright.ＰＥＮＡＮＡyv9fcMn4BR
1065Please respect copyright.ＰＥＮＡＮＡ7E5hA3NvzH
（圖5）Uromodulin在尿液的大量存在，將會強迫致病的大腸桿菌聚在一起，以免大腸桿菌能夠與膀胱內壁接觸及進行感染。1065Please respect copyright.ＰＥＮＡＮＡkZrwSTM6Hk
1065Please respect copyright.ＰＥＮＡＮＡQhaC8UA3QA
1065Please respect copyright.ＰＥＮＡＮＡPOoZPHtRRn
以壓倒性的數量，簡單將致病的大腸桿菌聚集及封鎖在一起，這種防禦機制相對地直接簡單。1065Please respect copyright.ＰＥＮＡＮＡwfbtStxvUX
至於Uromodulin能否與所有已知的致命細菌結合、會否有著其他的機制及功能，還需要進一步的調查。1065Please respect copyright.ＰＥＮＡＮＡNtu6PcfuRs
1065Please respect copyright.ＰＥＮＡＮＡ6JD53pCU1F
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。1065Please respect copyright.ＰＥＮＡＮＡtEAF6pNJZG
1065Please respect copyright.ＰＥＮＡＮＡcWqLZEmGJx
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc1065Please respect copyright.ＰＥＮＡＮＡFJHljaNAs4
1065Please respect copyright.ＰＥＮＡＮＡG4GBmfL3XK
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。1065Please respect copyright.ＰＥＮＡＮＡcRIzP3FHK6
1065Please respect copyright.ＰＥＮＡＮＡG8x75N4Y7O
Link:1065Please respect copyright.ＰＥＮＡＮＡ9yu7pKtHIg
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio1065Please respect copyright.ＰＥＮＡＮＡFQDbFgsbWb
1065Please respect copyright.ＰＥＮＡＮＡsDsMfmnRTD
1065Please respect copyright.ＰＥＮＡＮＡoHIclTVrC2
有興趣接收科普資訊的話，歡迎follow IG: potatopigtongue。1065Please respect copyright.ＰＥＮＡＮＡSNrOSYfoZq
1065Please respect copyright.ＰＥＮＡＮＡC1Y8xMXo6F
Ref1:https://science.sciencemag.org/content/369/6506/1005?ijkey=e112b23dc73c7c7bd746a5711869e4bf44026346&keytype2=tf_ipsecsha
10
ns18.219.66.32da2
